Green Synthesis of Symmetrical 1, 3-Disubstituted Urea Derivatives from Biuret and Different Substituted Anilines in the Presence of NaCl
نویسنده
چکیده
Rapid synthesis of symmetrical 1, 3disubstituted urea derivatives from biuret and different substituted anilines has been carried out in presence of Sodium chloride (NaCl) in dry media. Diverse substituted anilines were reacted with biuret in 2:1 molar ratio to give the corresponding urea derivatives. The reaction conditions were clement, solvent free, mild and the products were attained in good to excellent yields. Structural confirmations of all the products were done on the basis of spectroscopic analyses1 H NMR, 13 C NMR, IR and by assessment of their melting points with those of authentic samples.
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